Research Groups

Wouter de Laat Group

Biomedical genomics

Our Focus

Cancer and hereditary diseases are often the consequence of genetic alterations in non-coding DNA sequences that cause aberrant expression of disease-associated genes. The aim of our group is to understand how non-coding DNA sequences control gene expression in development and disease. We pioneer the development and application of innovative strategies to uncover the three-dimensional folding of DNA inside cells, which facilitates wiring regulatory DNA elements to disease-causing genes and thus enables assigning function to healthy and mutated genomes. Additionally, we develop improved gene sequencing methodologies that better enable the identification of disease-causing mutations in patients in order to facilitate the implementation of personalized disease therapy strategies. 

Amin Allahyar Post Doc
Carien Hilvering Phd Student
Carlo Vermeulen Phd Student
Christian Valdes Post Doc
Erica Vos Phd Student
Geert Geeven Post Doc
Marjon Verstegen Technician
Mark Pieterse Technician
Milan Sharma Technician
Niels Rinzema Phd Student
Peter Krijger Post Doc
Valerio Bianchi Post Doc
Yike Huang Phd Student
Contact Information
Wouter de Laat Oncode Investigator

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