Wouter de Laat Group

Biomedical genomics

Our Focus

Cancer and hereditary diseases are often the consequence of genetic alterations in non-coding DNA sequences that cause aberrant expression of disease-associated genes. The aim of our group is to understand how non-coding DNA sequences control gene expression in development and disease. We pioneer the development and application of innovative strategies to uncover the three-dimensional folding of DNA inside cells, which facilitates wiring regulatory DNA elements to disease-causing genes and thus enables assigning function to healthy and mutated genomes. Additionally, we develop improved gene sequencing methodologies that better enable the identification of disease-causing mutations in patients in order to facilitate the implementation of personalized disease therapy strategies.

Anna Karina Felder Phd Student
Amin Allahyar Post Doc
Diana Braat Technician
Iwan Vaandrager Phd Student
Konstantinos Sofiadis Post Doc
Leonela Luce Post Doc
Marjon Verstegen Technician
Peter Krijger Post Doc
Ruiqi Han Phd Student
Sjoerd Tjalsma Phd Student
Yike Huang Phd Student
Contact Information
Wouter de Laat Oncode Investigator

More Research

Research Strategy
Focus and Approach
Over 800 scientists working under a single strategy. Oncode is all about uniting efforts and bringing focus to research.
Support Programme
Our supporting programmes
New plans that help fulfil Oncode's objectives get our full support. Young talents are matched with mentors on the basis of their personal endeavours.