Thijn Brummelkamp Group

Experimental biomedical genetics

Our Focus

Our group develops and uses genetic approaches to study processes related to human disease. Recently we have developed an entirely novel genetic model system to expand the toolbox for genetics in human cells. This method enables efficient inactivation of human genes by a single mutation using insertional mutagenesis in cells that are haploid or near-haploid. We have used haploid genetic screens to identify genes that play a role in human disease. Recently we described a new step in the cellular entry route of picornaviruses, a long-sought enzyme that modifies microtubules, an off-switch in the GPCR signaling pathway and a new component of the PD1-PDL1 axis.

Abdelghani Mazouzi Post Doc
Danielle Bianchi Phd Student
Gian-Luca McLelland Post Doc
Lisa van den Hengel Technician
Nicolaas Boon Phd Student
Contact Information
Thijn Brummelkamp Oncode Investigator

More Research

Research Strategy
Focus and Approach
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Support Programme
Our supporting programmes
New plans that help fulfil Oncode's objectives get our full support. Young talents are matched with mentors on the basis of their personal endeavours.