Sjoerd van der Burg Group

Immunotherapy; T-cells; immune regulation; clinical trials

Our Focus

The white blood cells of the immune system play an important role in the outgrowth and elimination of cancer cells. Modulation of the immune system to treat cancer, also called immunotherapy, is currently regarded as the most innovative cancer therapy. My group “Experimental Cancer Immunology and Therapy” focuses on the factors of host-tumor interactions that determine the success and failure in immune control of cancer with the final aim to improve immunotherapeutic strategies against solid tumors.

We employ in vitro models, animal models and patient cohort studies to study the different molecular mechanisms that underlie the attraction, activation, suppression and antitumor efficacy of the different types of tumor-infiltrating immune cells, in particular T cells and myeloid cells. We want to understand how this is influenced by the tumor-immune context, the type of therapy (including chemotherapy, radiotherapy and targeted therapy) and the success of therapy achieved (cure, partial regression, stable disease).

Finally, we perform small clinical trials for first-in-man proof that newly designed strategies to positively influence the antitumor response work as we intended through comprehensive state-of-the-art immune monitoring.

Ziena Abdulrahman Arts-onderzoeker
Anouk Stolk Technician
Büşra Göynük Technician
Lien van der Minne Lab Manager
Camilla Labrie Technician
Els Verdegaal Assistant Professor
Vanessa van Ham Technician
Jim Middelburg Phd Student
Linda de Bruin Technician
Lisa Griffioen Research Assistant
Marij Welters Assistant Professor
Marjolein Sluijter Technician
Marit van Elsas Phd Student
Nikki Loof Technician
Christianne Groenveldt Phd Student
Sanne Boekestijn Technician
Saskia Santegoets Post Doc
Thorbald van Hall Assistant Professor
Contact Information
Sjoerd van der Burg Oncode Investigator

More Research

Research Strategy
Focus and Approach
Over 800 scientists working under a single strategy. Oncode is all about uniting efforts and bringing focus to research.
Support Programme
Our supporting programmes
New plans that help fulfil Oncode's objectives get our full support. Young talents are matched with mentors on the basis of their personal endeavours.