Monika Wolkers Group

T cell effector function, post-transcriptional gene regulation, RNA binding proteins

Our Focus

In the past decade it has become appreciated that the immune system is a prime player in anti-tumoral responses. In particular the role of T cells herein was shown to be critical. My lab studies how T cell responses against tumors and infections are generated and maintained. We specifically study the role of post-transcriptional gene regulation herein. To tackle this, we use two model systems. Mouse models allow us to study the fundamental aspects of T cell responses against ongoing infections and tumor challenges. In addition, with our study on tumor-reactive human T cells, we can now translate our findings from model systems to clinically relevant models, and investigate how T cell effector function can be maintained against tumors.

Aurelie Guislain Technician
Anouk Jurgens OIO
Benoit Nicolet OIO
Branka Popovic Post Doc
Iosifina Foskolou Post Doc
Nandhini Kanagasabesan Technician
Nikolina Sostaric Bioinformatician
Nordin Zandhuis OIO
Suzanne Castenmiller Technician
Sander Engels Technician
Contact Information
Monika Wolkers Oncode Investigator

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