Maarten van Lohuizen Group

Transcriptional repression

Our Focus

Our lab has a long-standing interest in epigenetic gene regulation dictated by chromatin modifications. Main themes are to study the mechanism of stable inherited transcriptional repression by Polycomb-group (Pc-G) protein complexes, and the effects of deregulation of Pc-G genes on development, Cell cycle control, cancer formation and stem cell maintenance. In addition, we are performing large-scale genetic screens in primary cells and in cancer-predisposed mice to identify cancer-relevant combinations of collaborating oncogenes and tumor-suppressor genes.

Members
Maarten van Lohuizen Oncode Investigator
Daniëlle Hulsman Technician
Elisabetta Citterio Senior Researcher
Ellen Tanger Technician
Gaurav Pandey Post Doc
Gayathri Chandrasekaran Post Doc
Jawahar Kopparam Post Doc
Martijn Koppens Phd Student
Michela Serresi Post Doc
Santiago Gisler Phd Student
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Contact Information
Maarten van Lohuizen Oncode Investigator
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