27 March 2020
In memoriam: Anjo van Heijst
We received the sad news that Anjo van Heijst passed away on March 23. Anjo was one of the first patient representatives of Oncode’s Clinical Advisory Board. With her knowledge and enthusiasm, she contributed immensely to the development of our clinical programmes. She was also a driving force behind Werkgroep Darmkanker, a platform for patients with colon cancer and their loved ones.
20 March 2020
Two New Clinical Proof-of-Concept Projects Funded by Oncode Institute
Oncode Institute aims to link fundamental and clinical research to enable efficient translation of promising findings into novel diagnostic methods and clinical treatment strategies. We are pleased to announce that the 9th and 10th grant within the Clinical Proof of Concept programme have been awarded.
19 March 2020
Therapeutic vaccine boosts survival rate in cervical cancer patients
A therapeutic vaccine against HPV-16 (type 16 human papillomavirus) improves the survival rate in cervical cancer patients. A new study by Oncode Investigator Sjoerd van der Burg and others shows that this vaccine produces a more robust response if it is combined with chemotherapy. The results of this study have been published in the journal Science Translational Medicine.
17 March 2020
The Oncode Compound Library: find new therapeutic applications that others missed
Oncode’s newly acquired Drug Repurposing Library is now available to all Oncode researchers, through the Drug Repurposing Programme. The library encompasses more than 6.000 unique compounds in different stages of clinical development. Each of them has extensively curated annotations, including details about commercial sources. Besides access to the library, Oncode will provide the technical infrastructure and expertise needed to perform complex compound screens.
13 March 2020
New research model: mini-tumors of the kidney
Exciting new research from Oncode Investigator Jarno Drost (Princess Máxima Center) on childhood kidney tumors. His group succeeded in establishing organoid cultures, derived from a variety of different childhood kidney tumors, which can be used to study the biology of non- Wilms tumors as well as to test new medication. These results have been published in Nature Communications.
11 March 2020
Spotlight on Breast Cancer: looking back at our first clinical workshop this year
Throughout the year, Oncode Institute organizes various workshops and trainings to share knowledge and facilitate collaboration. Organized in Jaarbeurs, Utrecht - the Breast Cancer Workshop was the first clinical workshop this year.
9 March 2020
Highlights from the Tumour Microenvironment and Immunology Meeting
Throughout the year, Oncode Institute organizes various workshops and trainings to share knowledge and facilitate collaboration. Together with Oncode Investigators Leila Akkari, Monika Wolkers and Jacques Neefjes, we recently organized the Tumour Microenvironment and Immunology Meeting in Veenendaal.
27 February 2020
A common gut microbe secretes a carcinogen
Cancer mutations can be caused by common gut bacteria carried by many people. This was demonstrated by researchers from the groups of Oncode Investigators Hans Clevers (Hubrecht Institute - KNAW) and Ruben van Boxtel (Princess Máxima Center).
27 February 2020
New colleagues at Oncode Institute
We are pleased to inform you about our new Oncode colleagues. Bianca-Olivia Nita started as a project communication manager, Jacqueline Staring is our new Program Manager and Evi Kallinikou joined as our new paralegal. We asked them to describe their role within Oncode briefly.
27 February 2020
Oncode Clinical Proof of Concept projects – status update
To support (pre)clinical projects, Oncode launched the Clinical Proof of Concept (CPoC) fund with an open call for proposals. One of the first projects that has received CPoC funding is ‘Head and neck cancer organoids and their potential to predict patient therapy response’ - a collaboration between the Hubrecht Institute, UMC Utrecht and Hubrecht Organoid Technology (HUB). We asked Else Driehuis - postdoc in Oncode Investigator Hans Clevers’ lab and Tech Transfer Scientist at HUB - about the progress and her experience with working on this project.
Scroll for more