27 May 2020

New facilities available for Oncode researchers

Elize Brolsma
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Elize Brolsma

Elize is part of Oncode’s communication team. She has over 10 years of experience in the com-munication industry, both for commercial and non-profit organisations. After obtaining her bache-lor and master degree in communication at Utrecht University, Elize worked as a communication professional at a research institute, PR agency, law firm and internet company. She has a strong focus on external communications and Public Relations. At Oncode - together with her colleagues - Elize produces the monthly newsletters for Oncode Investigators & Researchers and the Oncode digital magazine. She publishes content for the Oncode website and is responsible for all social media channels. She enjoys discussing science with researchers and support them in their outreach.

We are pleased to announce that three facilities are now open to the whole Oncode research community. The goal of Oncode Institute is to translate the results of ground-breaking fundamental research into the clinic faster, in order to improve the chances of cancer patients. Instead of competition between scientists, Oncode encourages collaboration. Investing in facilities which can be used by all Oncode researchers, is one of the ways in which Oncode wants to contribute to breakthroughs in cancer research.

Proteomics for Oncode
Location: UMC Utrecht
Contact persons: Boudewijn Burgering and Michiel Vermeulen
Diseases such as cancer are characterized by cellular heterogeneity. This facility offers a state-of-the-art proteomics by measuring the full protein and/or metabolite composition. In the future this facility will be complemented with single cell proteomics.

Proteins4Oncode
Location: NKI
Contact person: Anastassis Perrakis
The Protein Facility will support Oncode researchers with expressing and purifying proteins, characterising them (quality control), and crystallising them for X-ray analysis. This facility can also help researchers measure their interactions with other proteins, nucleic acids, lipids, carbohydrates, and small molecules. Finally, the facility supports in setting up and optimising activity assays.

Oncode Antibody biologics accelerator platform UMAB
Location: UMC Utrecht
Contact person: Linde Meyaard and Jeanette Leusen
The goal of this facility is to work closely with researchers to develop new monoclonal antibodies, suited for specific basic research or clinical applications. UMAB employs a new and very efficient cellular immunization method in mice. With this method, antibodies can be raised against for instance low immunogenic membrane proteins. In addition, UMAB can make antibodies against conformational epitopes and generate agonistic and antagonistic antibodies.

Jacqueline Staring Programme Manager
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Jacqueline Staring

Programme Manager

After her study of Biomedical Sciences at Utrecht University, Jacqueline finished her PhD in virology and functional genetics at the Netherlands cancer institute. She then moved to Denmark to do a postdoc in ancient pathogens and genomics at the University of Copenhagen. At Oncode, Jacqueline is working on the technology focussed programmes such as the Drug Repurposing, Equipment & Infrastructure, and Technology Access programmes. She also likes to engage the younger Oncode community and is therefore for instance co-organizing the Oncode postdoc retreats.

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