Proteomics facility; Proteomics for Oncode (UMC Utrecht)

Keywords: single-cell proteomics, measuring the full protein and/or metabolite composition

Location: UMC Utrecht
Contact person: Boudewijn Burgering and Michiel Vermeulen

If you would like to make use of this facility, please send an e-mail to Proteomics4Oncode@science.ru.nl

How it can help you

Diseases such as cancer are characterized by cellular heterogeneity. This facility offers a state-of-the-art single-cell proteomics by measuring the full protein and/or metabolite composition of a single cell.

The Proteomics4Oncode facility operates four state-of-the-art, high-resolution instruments: an Orbitrap Tribrid Eclipse, 2 Orbitrap Tribrid Fusion instruments and an Orbitrap Exploris 480.These mass spectrometers can be used for a broad variety of applications, ranging from quantitative whole proteome measurements to post-translational modification (PTM) analyses (phospho, acetyl, etc.) and affinity purification of protein complexes. Next to these standard workflows we are also open to work with our customers on customized approaches to address specific questions such as protein or PTM turnover experiments or absolute whole proteome measurements. Furthermore, Proteomics4Oncode provides advice to help you design the best possible experimental setup for your research question. Finally, automated phospho-enrichment and offline chromatography workflows are also available upon request.

More information on Proteomics for Oncode website

For further information, please contact Jacqueline Staring, programme manager at Oncode.

Jacqueline Staring

Jacqueline Staring

Programme Manager

After her study of Biomedical Sciences at Utrecht University, Jacqueline finished her PhD in virology and functional genetics at the Netherlands cancer institute. She then moved to Denmark to do a postdoc in ancient pathogens and genomics at the University of Copenhagen. At Oncode, Jacqueline is working on the technology focussed programmes such as the Drug Repurposing, Equipment & Infrastructure, and Technology Access programmes. She also likes to engage the younger Oncode community and is therefore for instance co-organizing the Oncode postdoc retreats.


Programme Manager