21 October 2021
In memoriam: David Morse Livingston, MD
Oncode Institute and its research community were saddened by the news of the unexpected death of David M. Livingston, MD. Livingston was the Deputy Director of the Dana-Farber/Harvard Cancer Center; Chief of the Charles A. Dana Division of Human Cancer Genetics, and the Emil Frei Professor of Genetics and Medicine at Harvard Medical School. He was also the chair of Oncode’s International Advisory Board.
21 October 2021
Oncode Institute supports new preclinical collaboration between HepaRegeniX and the NKI
HepaRegeniX GmbH, a clinical stage company developing novel therapies for the treatment of acute and chronic liver diseases, announced a collaboration with the NKI to investigate HepaRegeniX’ new drug candidate HRX-0233 in preclinical in vivo models with Kirsten rat sarcoma virus (KRAS) mutant tumors. Oncode’s Valorization Team supported the contract negotiations.
19 October 2021
New research uncovers growth dynamics of pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease and patients diagnosed with PDAC have a very poor prognosis. It has been speculated that a rare population of cancer stem cells (CSCs) are responsible for tumor growth, therapy resistance, and rapid metastatic progression in PDAC. The purported CSC populations were discovered by in vitro clonogenic assays and transplantation assays in mice. However, their relevance in established PDAC tissue has not been determined. Importantly these assays were mostly dependent on the expression of a specific marker, therefore the functionality of cell populations not expressing these markers remained untested. A new study by Oncode Investigator Louis Vermeulen and co-investigators Sophie Lodestijn and Maarten Bijlsma (all Amsterdam UMC), published today in Cell Reports, changes that. Their results can have important implications for the treatment of PDAC.
12 October 2021
“I need to know that what I do matters”
Despite her busy schedule, physician-scientist, gastroesophageal cancer specialist and Oncode Investigator Sarah Derks (Amsterdam UMC, VUmc site) took time out to participate in the Darm to Darm cycling challenge: a charity biking race from Amsterdam to Darmstadt (Germany). What motivated her to do so, and what makes her tick both professionally and personally?
1 October 2021
Two Oncode researchers win the International Birnstiel Award
Oncode Institute is proud to announce that two Oncode researchers have won the 2021 International Birnstiel Award for Doctoral Studies in Molecular Life Sciences. Sanne Boersma (Hubrecht Institute, Marvin Tanenbaum Group) and Sanne van Neerven (Amsterdam University Medical Center, Louis Vermeulen Group) are among the six winners this year.
Fundamental science, clinical testing and a sharp mind for market opportunities: at Oncode we bring it all together to create impact for patients.
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