7 September 2021
Evidence for safety: stem cell transplants do not lead to changes in the DNA
A new study from the group of Oncode Investigator Ruben van Boxtel shows that stem cell transplants do not lead to changes in the DNA of the donor cells. This conclusion provides important evidence for the safety of this procedure. Stem cell transplants can form part of the treatment for children with certain types of leukemia.
1 September 2021
Oncode Institute co-lead of major consortium studying therapy resistance in cancer
90% of people who die from cancer respond well to the first treatment, but the cancer is fatal upon its return. In these cases, the tumor has often become resistant to the treatment that initially worked. PERSIST-SEQ, a new international consortium of academic and industry experts in cancer research, will spend the next 5 years intensively investigating why cancer often returns after treatment.
26 August 2021
The added value and simplicity of data management: the how, the why and what sound data management can bring to your lab
Making it transparent, reproducible, re-usable – the benefits of good data management are manifold. In Monique den Boer’s lab at the Princess Máxima Center for pediatric oncology, the structured practices of data management are now part of the lab’s culture. This has brought not only a wealth of data that everyone can use, but also various international collaborations and publications. We spoke to Judith Boer, long-time data steward within the lab, about the easy but efficient structure she devised and implemented, and the challenges and long-term benefits of storing data well.
9 August 2021
New research reveals that the actionable metastatic cancer genome is remarkably stable
A one-time analysis of the entire tumor DNA is almost always sufficient to find all DNA errors that may be relevant for treating metastatic cancer. This is because actionable DNA errors remain remarkably stable over time, despite treatment with drugs. This discovery was made by Oncode Investigator Emile Voest (NKI) and his team at the Netherlands Cancer Institute, with the financial support of Oncode Institute. Their findings are now published in Nature Medicine.
5 August 2021
Absence of stem cells in pancreas changes view on pancreatic cancer
New research by Oncode Investigator Louis Vermeulen and co-investigator Maarten Bijlsma shows that there are no stem cells in the pancreas. These unexpected findings potentially have major implications for pancreatic cancer research, since stem cells are often at the root of tumor development. This research was published today in the leading journal Cell Stem Cell.
Fundamental science, clinical testing and a sharp mind for market opportunities: at Oncode we bring it all together to create impact for patients.
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