19 August 2022
(Future) researchers and patients join forces to make true impact
For the second year in a row, Oncode’s Patient Engagement Programme had the opportunity to contribute to the bachelor course ‘Eye for Impact’ for biomedical sciences students at University Medical Center Utrecht (UMCU). A unique example of how to give substance to patient engagement in basic research. Oncode researchers and patient representatives participated in a series of lectures and interactive sessions, where the students experienced first-hand how patients and researchers can partner up.
10 August 2022
Unravelling genetic mechanism behind tumor formation can improve targeted treatment
New research by the group of Jos Jonkers explains variation in treatment response to FGFR2 inhibitors and provides a way to improve targeted therapy for cancer patients. Their work highlights the importance of analyzing the functional consequences of genetic variants found in tumors.
4 August 2022
Chemotherapy speeds up DNA-level aging
Chemotherapy is an important part of treatment for children with cancer, contributing to the recovery of more and more children. Childhood cancer survivors do sometimes experience late effects from their treatment, including a higher risk of developing a second cancer. That risk is very small, but about five to six times greater than in the ‘normal’ population. In new research, published in Cancer Discovery, the team of Oncode Investigator Ruben Van Boxtel (Princess Máxima Center) shows that accelerated DNA aging turns out to be the main cause of the harmful effect of chemotherapy treatment.
4 August 2022
Paving the way for targeted therapy development for peritoneal metastases in colorectal cancer
Many patients with colorectal cancer suffer from metastases in the abdominal cavity, which have a big impact on quality of life and lead to poor survival. The team of Oncode Investigator Louis Vermeulen and collaborators have now shown that peritoneal metastases occur almost exclusively in a particular type of colon cancer: CMS4. With their research, published in Nature Communications, the team is now able to explain why and how this type of colon cancer can metastasize to the peritoneum.
29 July 2022
A new European strategic initiative to better understand cancer: 4.UNCAN.eu is calling for experts!
4.UNCAN.eu is launching a “Call for Expert Working Groups” (EWGs). Scientific leaders with expertise in 6 different areas of cancer research will be invited to help identify the research priorities that need to be addressed to reach a new level of understanding in cancer. These research priorities are intended to serve as guidelines for the European Scientific Community (including the Cancer Mission Board) to set specific calls for funding, as well as use cases to feed a European Federated Cancer Research Data Hub.
Fundamental science, clinical testing and a sharp mind for market opportunities: at Oncode we bring it all together to create impact for patients.
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