27 January 2023
Eerste live bijeenkomst Oncode Patiënt Perspectief Programma brengt (ex-)patiënten en onderzoekers dichter bij elkaar
(Text in Dutch) Benieuwd hoe onderzoekers en (ex)patiënten elkaar kunnen helpen? Lees de highlights over Oncode's Patiënt Perspectief Programma meeting, waar onderzoekers en patiënt partners elkaar ontmoetten.
11 January 2023
Specialized immune cells carry potential for new cancer immunotherapies
Oncode Investigators Emile Voest, Ton Schumacher and Lodewyk Wessels (all NKI), together with scientists from Leiden University Medical Center (LUMC) have discovered how specialized immune cells can detect and remove cancers that are ‘invisible’ to the conventional defense mechanisms of the immune system. The findings could lead to novel cancer immunotherapies. Their work is published today in Nature.
2 January 2023
New technique to detect T cells that recognize a patient’s tumor
Oncode Investigators Emile Voest and Ton Schumacher together with Wouter Scheper (all NKI) have developed a new technique that can map out molecules on the tumor cells in individual cancer patients that are recognized by T cells. This new technology is an important step toward personalized immunotherapy. Their findings were published today in Nature Biotechnology.
15 December 2022
Overlooked immune cell proves important for impact of immunotherapy
An open mind and the courage to go off the beaten track has led Oncode Investigator Karin de Visser and medical oncologist and researcher Marleen Kok (both at the NKI) to a surprising finding. They discovered that one type of immune cell, one that cancer researchers rarely look at, is actually of great importance. Their finding could be crucial for patients receiving immunotherapy, such as breast cancer patients. Their research paper was published today in Cancer Cell.
24 November 2022
AlphaFill: filling in the blanks in protein structure prediction
The development of tools like AlphaFold and RoseTTAfold, and more recently of the ESM Metagenomic Atlas and OmegaFold, was a gamechanger in the field of 3D protein structure prediction. However, for many proteins a pivotal piece to the puzzle was still lacking, as most proteins do not function without specific cofactors. New work by the group of Oncode Investigator Anastassis Perrakis at the Netherlands Cancer Institute literally fills this void and brings AlphaFill into the picture. Their work was published today in Nature Methods.
Fundamental science, clinical testing and a sharp mind for market opportunities: at Oncode we bring it all together to create impact for patients.
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